T J Chambers

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.

T J Chambers, Ronald C. Weir, Arash Grakoui et al. · Proceedings of the National Academy of Sciences · 1990 · 350 citations · Full text

Virus Structure, Viral Replication, Sequence Homology +15

Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation.

Charles M. Rice, Arash Grakoui, Ricardo Galler et al. · PubMed · 1989 · 296 citations

Viral Replication, Molecular Virology, Yellow Fever +14

Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites

T J Chambers, Arash Grakoui, Charles M. Rice · Journal of Virology · 1991 · 242 citations · Full text

Viral Replication, Molecular Virology, Natural Sciences +12

Recombinant Chimeric Yellow Fever-Dengue Type 2 Virus Is Immunogenic and Protective in Nonhuman Primates

Farshad Guirakhoo, Richard Weltzin, T J Chambers et al. · Journal of Virology · 2000 · 224 citations · Full text

Dengue-2 Virus, Viral Pathogenesis, Immunology +17

Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication

T J Chambers, Ann Nestorowicz, Sean M. Amberg et al. · Journal of Virology · 1993 · 191 citations · Full text

Viral Replication, Viral Polymerase Mechanism, Immunology +16