Safety and Efficacy of Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine Formulations in Nonhuman Primates

Farshad Guirakhoo, Z. Zhang, Gene Myers, +15

Journal of Virology

Synthetic VirologyImmunologyDen Virus SerotypesNonhuman PrimatesPathogen Discovery +14

Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model

Christian W. Mandl, Farshad Guirakhoo, Heidemarie Holzmann, +2

Journal of Virology

Distinct EpitopesVirus StructureMolecular VirologyAllergyNeurovirology +13

A live, attenuated recombinant West Nile virus vaccine

Thomas P. Monath, Jian Liu, Niranjan Kanesa-thasan, +13

Proceedings of the National Academy of Sciences

VaccinationMolecular VirologyVaccine DevelopmentVaccine TargetPathogenesis +10

Recombinant Chimeric Yellow Fever-Dengue Type 2 Virus Is Immunogenic and Protective in Nonhuman Primates

Farshad Guirakhoo, Richard Weltzin, T J Chambers, +7

Journal of Virology

Dengue-2 VirusViral PathogenesisImmunologyNonhuman PrimatesVirus Transmission +15

Construction, Safety, and Immunogenicity in Nonhuman Primates of a Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine

Farshad Guirakhoo, Juan Arroyo, Catherine Miller, +8

Journal of Virology

ImmunologyNonhuman PrimatesVirus TransmissionYf Virus-immuneArbovirus +14

Clinical proof of principle for ChimeriVax™: recombinant live, attenuated vaccines against flavivirus infections

Thomas P. Monath, Karen McCarthy, Philip Bedford, +8

Vaccine

VaccinationVaccine DevelopmentVaccine ResearchImmunologyVirology +5

Chimeric Live, Attenuated Vaccine against Japanese Encephalitis (ChimeriVax‐JE): Phase 2 Clinical Trials for Safety and Immunogenicity, Effect of Vaccine Dose and Schedule, and Memory Response to Challenge with Inactivated Japanese Encephalitis Antigen

Thomas P. Monath, Farshad Guirakhoo, Richard Nichols, +9

The Journal of Infectious Diseases

The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of E glycoprotein

Farshad Guirakhoo, Richard A. Bolin, John T. Roehrig

Virology

Virus StructureMolecular VirologyMedicineNatural SciencesPathogenesis +8

Live Attenuated Chimeric Yellow Fever Dengue Type 2 (ChimeriVax™-DEN2) Vaccine: Phase I Clinical Trial for Safety and Immunogenicity: Effect of Yellow Fever Pre-immunity in Induction of Cross Neutralizing Antibody Responses to All

Farshad Guirakhoo, Scott Kitchener, Dennis Morrison, +11

Human Vaccines

Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions

Farshad Guirakhoo, Franz X. Heinz, Christian W. Mandl, +2

Journal of General Virology

Membrane FusionVector-borne PathogenLangat VirusViral ReplicationMolecular Virology +11