Optimization of humanized IgGs in glycoengineered Pichia pastoris

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Raphael Clynes, Terri L. Towers, Leonard G. Presta et al. · Nature Medicine · 2000 · 2.7K citations

Medicine, Cancer Biology, Oncology +15

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene

Guillaume Cartron, Laurent Dacheux, Gilles Salles et al. · Blood · 2002 · 1.9K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity

Robert L. Shields, Jadine Lai, Rodney G. Keck et al. · Journal of Biological Chemistry · 2002 · 1.8K citations · Full text

Life Sciences, Biochemistry, Immunology +16

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +17

High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR

Robert L. Shields, Angela K. Namenuk, Kyu Hong et al. · Journal of Biological Chemistry · 2001 · 1.2K citations · Full text

Pharmacy, Immunology, Molecular Biology +17