Concepedia

Host Cell Glycoengineering

Host Cell Glycoengineering is a glycoengineering strategy that involves the targeted modification of glycosylation machinery within host cells to achieve precise control over the glycan structures synthesized during recombinant protein production.

95

Publications

6.7K

Citations

511

Authors

183

Institutions

Publications per year

2017–2026

14

Parents

Publications

95

Enhancement of therapeutic protein in vivo activities through glycoengineering

Steve Elliott, Tony Lorenzini, Sheilah Asher et al. · Nature Biotechnology · 2003 · 516 citations

, , +14

Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity

J. Couceiro, James C. Paulson, Linda G. Baum · Virus Research · 1993 · 456 citations

, , +17

Optimization of humanized IgGs in glycoengineered Pichia pastoris

Huijuan Li, Natarajan Sethuraman, Terrance A. Stadheim et al. · Nature Biotechnology · 2006 · 427 citations

, , +12

A novel pathway for glycan assembly: Biosynthesis of the glycosyl-phosphatidylinositol anchor of the trypanosome variant surface glycoprotein

Wayne J. Masterson, Tamara L. Doering, Gerald W. Hart et al. · Cell · 1989 · 312 citations

, , +15

Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant

Shunji Natsuka, Kevin M. Gersten, K Zenita et al. · Journal of Biological Chemistry · 1994 · 311 citations · Full text

, , +14

1–5 of 95

Authors

511

  1. TA
    Terrance A. Stadheim

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    5 publications · 662 citations

    5

    h-index

  2. MC
    Michael Cukan

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    4 publications · 628 citations

    4

    h-index

  3. HL
    Huijuan Li

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    4 publications · 505 citations

    4

    h-index

  4. NS
    Nathan Sharkey

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    4 publications · 93 citations

    4

    h-index

  5. YJ
    Youwei Jiang

    Southern University of Science and Technology, China

    4 publications · 628 citations

    4

    h-index

1–5 of 511

Institutions

183

  1. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    6 h-index

    80 publications

    3.9K citations

  2. University of Washington

    Seattle, United States

    6 h-index

    19 publications

    670 citations

  3. The University of Queensland

    Brisbane, Australia

    3 h-index

    5 publications

    254 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    7 publications

    807 citations

  5. University of Wyoming

    Laramie, United States

    3 h-index

    8 publications

    274 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    1.6K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    6 publications

    110 citations

  8. Stanford University

    Stanford, United States

    3 h-index

    3 publications

    405 citations

1–8 of 183

Venues

  1. Virology

    14 publications · 494 citations

    12

    h-index

  2. Glycobiology

    5 publications · 208 citations

    5

    h-index

  3. Journal of Biological Chemistry

    JBC · 5 publications · 454 citations

    5

    h-index

  4. Journal of General Virology

    4 publications · 88 citations

    4

    h-index

  5. Journal of Virology

    JVI · 4 publications · 272 citations

    4

    h-index

1–5