Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR)

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Sunder Mudaliar, Robert R. Henry, Arun J. Sanyal et al. · Gastroenterology · 2013 · 906 citations

Metabolic Syndrome, Hepatology, Nonalcoholic Fatty Liver Disease +9

Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor

M Ananthanarayanan, Niranjan Balasubramanian, Makoto Makishima et al. · Journal of Biological Chemistry · 2001 · 781 citations · Full text

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Roberto Pellicciari, Stefano Fiorucci, Emidio Camaioni et al. · Journal of Medicinal Chemistry · 2002 · 722 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Selective Fxr Agonist +14

Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR

Patrick Maloney, Derek J. Parks, Curt D. Haffner et al. · Journal of Medicinal Chemistry · 2000 · 521 citations · Full text

Altmetric Attention Score, Molecular Biology, Research Triangle Park +19

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

Mitsuhiro Watanabe, Yasushi Horai, Sander M. Houten et al. · Journal of Biological Chemistry · 2011 · 248 citations · Full text

Obesity, Metabolic Syndrome, Body Composition +9