Derek J. Parks

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science · 1999 · 2.2K citations

Bile Acids, Molecular Physiology, Lipid Synthesis +14

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H. Eric Xu, Millard H. Lambert, Valerie G. Montana et al. · Molecular Cell · 1999 · 1.2K citations · Full text

Metabolic Syndrome, Lipid Synthesis, Biochemistry +1

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Randy K. Bledsoe, Valerie G. Montana, Thomas B. Stanley et al. · Cell · 2002 · 810 citations · Full text

Crystal Structure, Signal Transduction, Biochemistry +9

Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands

Linda B. Moore, Derek J. Parks, Stacey A. Jones et al. · Journal of Biological Chemistry · 2000 · 808 citations · Full text

Pregnane X Receptor, Signal Transduction, Pxr Activator Clotrimazole +15

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Roberto Pellicciari, Stefano Fiorucci, Emidio Camaioni et al. · Journal of Medicinal Chemistry · 2002 · 722 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Selective Fxr Agonist +14