Roberto Pellicciari

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.7K citations · Full text

Biochemistry, Biliary Tract, Liver Physiology +6

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Roberto Pellicciari, Stefano Fiorucci, Emidio Camaioni et al. · Journal of Medicinal Chemistry · 2002 · 722 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Selective Fxr Agonist +14

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

Thijs W.H. Pols, Mitsunori Nomura, Taoufiq Harach et al. · Cell Metabolism · 2011 · 558 citations · Full text

Inflammation, Vascular Disease, Immunology +9

The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis

Stefano Fiorucci, Elisabetta Antonelli, Giovanni Rizzo et al. · Gastroenterology · 2004 · 457 citations

Fibrosis, Signal Transduction, Hepatology +15

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

E. Wahlberg, T. Karlberg, E. Kouznetsova et al. · Nature Biotechnology · 2012 · 455 citations

Medicinal Chemistry, Drug Target, Tankyrase Inhibitors +13