Antimo Gioiello

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.7K citations · Full text

Biochemistry, Biliary Tract, Liver Physiology +6

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

Thijs W.H. Pols, Mitsunori Nomura, Taoufiq Harach et al. · Cell Metabolism · 2011 · 558 citations · Full text

Inflammation, Vascular Disease, Immunology +9

Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration

Giovanni Sorrentino, Alessia Perino, Gaby El Alam et al. · Gastroenterology · 2020 · 362 citations · Full text

Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies

Hiroyuki Sato, Antonio Macchiarulo, Charles Thomas et al. · Journal of Medicinal Chemistry · 2008 · 285 citations · Full text

Discovery of 6α-Ethyl-23(<i>S</i>)-methylcholic Acid (<i>S</i>-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity

Roberto Pellicciari, Antimo Gioiello, Antonio Macchiarulo et al. · Journal of Medicinal Chemistry · 2009 · 249 citations · Full text

Pharmaceutical Science, Pharmaceutical Chemistry, Molecular Pharmacology +18