Antonio Macchiarulo

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

Alban Bessede, Marco Gargaro, Maria Teresa Pallotta et al. · Nature · 2014 · 670 citations · Full text

Life Sciences, Molecular Genetics, Cell Signaling +11

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

E. Wahlberg, T. Karlberg, E. Kouznetsova et al. · Nature Biotechnology · 2012 · 460 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

Giada Mondanelli, Roberta Bianchi, Maria Teresa Pallotta et al. · Immunity · 2017 · 343 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies

Hiroyuki Sato, Antonio Macchiarulo, Charles Thomas et al. · Journal of Medicinal Chemistry · 2008 · 288 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9