T. Karlberg

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

E. Wahlberg, T. Karlberg, E. Kouznetsova et al. · Nature Biotechnology · 2012 · 460 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

A.G. Thorsell, T. Ekblad, T. Karlberg et al. · Journal of Medicinal Chemistry · 2016 · 372 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structural Basis for the Inhibition Mechanism of Human Cystathionine γ-Lyase, an Enzyme Responsible for the Production of H2S

Qingxiang Sun, R. Collins, Shufen Huang et al. · Journal of Biological Chemistry · 2008 · 206 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

K. Thangavelu, Catherine Pan, T. Karlberg et al. · Proceedings of the National Academy of Sciences · 2012 · 202 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78

M. Wisniewska, T. Karlberg, L. Lehtiö et al. · PLoS ONE · 2010 · 151 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11