Curt D. Haffner - Concepedia

Concepedia

Author

Curt D. Haffner

Research Triangle Park Foundation ORCID

Also Known As

C. D. HAFFNER, C. D. Haffner, C. HAFFNER, C.D. Haffner, Christian Häffner, Curt D. Haffner, Curt Haffner

36

Publications

1.7K

Citations

19

H-Index

55

Concepts

All Affiliations

Research Triangle Park Foundation GlaxoSmithKline (United States)GlaxoSmithKline (Netherlands)

CD

About

Curt D. Haffner is an author at Research Triangle Park Foundation specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	14	1.4K
2	Natural Sciences	10	10	1.2K
3	Engineering	3	3	133
4	Health Sciences	1	1	43
5	Applied Physiology	1	1	43

Curt D. Haffner

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23

Publications

1.7K

Citations

19

H-Index

	Year	Citations
Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR Patrick Maloney, Derek J. Parks, Curt D. Haffner, Journal of Medicinal Chemistry Altmetric Attention ScoreMolecular BiologyResearch Triangle ParkChemical BiologyChemical Tool	2000	521
Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity Marcos L. Sznaidman, Curt D. Haffner, Patrick Maloney, Bioorganic & Medicinal Chemistry Letters Biological ActivityMolecular PharmacologyBiochemistryNatural SciencesMedicine	2003	311
Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors Curt D. Haffner, J. David Becherer, Eric E. Boros, Journal of Medicinal Chemistry Antiparasitic AgentNad LevelsPharmacotherapyMedicinal ChemistryNad Elevation	2015	127
Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP) Curt D. Haffner, Caroline J. Diaz, Aaron B. Miller, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryPyrrolidinyl PyridoneBiochemistryMedicine	2008	60
6-Azasteroids: Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Journal of Medicinal Chemistry PharmacotherapySelectivity Versus 3BhsdGlucocorticoidPharmaceutical ChemistryRat Model	1994	59
The Palladium-Catalyzed Enyne Cycloisomerization Reaction in a General Approach to the Asymmetric Syntheses of the Picrotoxane Sesquiterpenes. Part I. First-Generation Total Synthesis of Corianin and Formal Syntheses of Picrotoxinin and Picrotin Barry M. Trost, Curt D. Haffner, David J. Jebaratnam, Journal of the American Chemical Society Asymmetric SynthesesCatalyst SystemAsymmetric CatalysisEngineeringHeterocyclic	1999	53
6-Azasteroids: potent dual inhibitors of human type 1 and 2 steroid 5.alpha.-reductase Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Journal of Medicinal Chemistry Potent Dual InhibitorsMolecular PharmacologyMedicinal ChemistryHuman Type 1Biochemistry	1993	52
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38 J. David Becherer, Eric E. Boros, Tiffany Carpenter, Journal of Medicinal Chemistry PharmacotherapyChemical BiologyExperimental PharmacologyPharmaceutical ChemistryTranslational Pharmacology	2015	52
Structure-Based Design of Potent Retinoid X Receptor α Agonists Curt D. Haffner, James M. Lenhard, Aaron B. Miller, Journal of Medicinal Chemistry	2004	48
Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase by 6-Azaandrost-4-en-3-ones: Optimization of the C17 Substituent Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Journal of Medicinal Chemistry	1995	47

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