Concepedia

Programmable RNA recognition and cleavage by CRISPR/Cas9

Mitchell R. O’Connell, Benjamin L. Oakes, Samuel H. Sternberg, Alexandra East-Seletsky, Matias Kaplan, Jennifer A. Doudna

Nature · 2014 · 638 citations · 27 references

DOI

Concepts

References

27

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.3K citations

, , +17

Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Giedrius Gasiūnas, Rodolphe Barrangou, Philippe Horvath et al. · Proceedings of the National Academy of Sciences · 2012 · 2.8K citations · Full text

, , +14

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

Hiroshi Nishimasu, F. Ann Ran, Patrick D. Hsu et al. · Cell · 2014 · 2.4K citations · Full text

, , +15

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion et al. · Nature · 2010 · 2.3K citations

, , +11