Mitchell R. O’Connell

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

Alexandra East-Seletsky, Mitchell R. O’Connell, Spencer C. Knight et al. · Nature · 2016 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +9

Programmable RNA recognition and cleavage by CRISPR/Cas9

Mitchell R. O’Connell, Benjamin L. Oakes, Samuel H. Sternberg et al. · Nature · 2014 · 638 citations

Life Sciences, Genetics, Molecular Biology +12

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

David A. Nelles, Mark Y. Fang, Mitchell R. O’Connell et al. · Cell · 2016 · 534 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

Alexandra East-Seletsky, Mitchell R. O’Connell, David Burstein et al. · Molecular Cell · 2017 · 302 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +11

Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme

Gavin J. Knott, Alexandra East-Seletsky, Joshua C. Cofsky et al. · Nature Structural & Molecular Biology · 2017 · 175 citations · Full text

Life Sciences, Genetics, Molecular Biology +11