Alexandra East-Seletsky

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

Alexandra East-Seletsky, Mitchell R. O’Connell, Spencer C. Knight et al. · Nature · 2016 · 1.2K citations · Full text

Rna Processing, Natural Sciences, Molecular Biology +9

Programmable RNA recognition and cleavage by CRISPR/Cas9

Mitchell R. O’Connell, Benjamin L. Oakes, Samuel H. Sternberg et al. · Nature · 2014 · 631 citations

Programmable Rna Recognition, Molecular Biology, Gene Editing +4

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Glenn S. Cowley, Barbara A. Weir, Francisca Vázquez et al. · Scientific Data · 2014 · 412 citations · Full text

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

Alexandra East-Seletsky, Mitchell R. O’Connell, David Burstein et al. · Molecular Cell · 2017 · 291 citations · Full text

Molecular Biology, Genetic Engineering, Gene Editing +5

ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

Xingqi Chen, Ying Shen, Will E. Draper et al. · Nature Methods · 2016 · 280 citations · Full text

Long-read Sequencing, Functional Genomics, Next-generation Sequencing +10