Concepedia

Native-State Solubility and Transfer Free Energy as Predictive Tools for Selecting Excipients to Include in Protein Formulation Development Studies

Douglas D. Banks, Ramil F. Latypov, Randal R. Ketchem, Jon Woodard, Joanna L. Scavezze, Christine C. Siska, Vladimir I. Razinkov

Journal of Pharmaceutical Sciences · 2012 · 69 citations · 40 references

DOI

Concepts

References

40

Denaturant <i>m</i> values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding

Jeffrey K. Myers, C. Nick Pace, J. Martin Scholtz · Protein Science · 1995 · 1.7K citations · Full text

Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design

Erica Ollmann Saphire, Paul W.H.I. Parren, Ralph Pantophlet et al. · Science · 2001 · 923 citations

Conformation Changes of Proteins

Rufus Lumry, Henry Eyring · The Journal of Physical Chemistry · 1954 · 864 citations

, , +22

The Solubility of Amino Acids and Related Compounds in Aqueous Urea Solutions

Yasuhiko Nozaki, Charles Tanford · Journal of Biological Chemistry · 1963 · 668 citations · Full text

, , +5

The Peptide Backbone Plays a Dominant Role in Protein Stabilization by Naturally Occurring Osmolytes

Yufeng Liu, D. Wayne Bolen · Biochemistry · 1995 · 453 citations