Concepedia

Protein Formulation Engineering

Protein Formulation Engineering is the academic discipline within therapeutic protein engineering that focuses on the systematic design and optimization of protein formulations to ensure stability, bioavailability, and manufacturability, distinguishing itself from related subfields by emphasizing excipient selection, buffer conditions, and delivery modalities critical for therapeutic efficacy and shelf life.

139

Publications

7.2K

Citations

542

Authors

201

Institutions

Publications per year

2017–2026

42

Parents

Publications

139

Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy

Sie Huey Lee, Desmond Heng, Wai Kiong Ng et al. · International Journal of Pharmaceutics · 2010 · 400 citations

, , +17

Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity

Peng Zhang, Fang Sun, Caroline Tsao et al. · Proceedings of the National Academy of Sciences · 2015 · 309 citations · Full text

, , +17

Finding better protein engineering strategies

Romas J. Kazlauskas, Uwe T. Bornscheuer · Nature Chemical Biology · 2009 · 222 citations

, , +10

Heating-Aided pH Shifting Modifies Hemp Seed Protein Structure, Cross-Linking, and Emulsifying Properties

Qingling Wang, Yan Jin, Youling L. Xiong · Journal of Agricultural and Food Chemistry · 2018 · 190 citations

, , +17

Effect of Mannitol Crystallization on the Stability and Aerosol Performance of a Spray-Dried Pharmaceutical Protein, Recombinant Humanized anti-IgE Monoclonal Antibody

Henry R. Costantino, James D. Andya, Phuong‐Anh T. Nguyen et al. · Journal of Pharmaceutical Sciences · 1998 · 167 citations

, , +17

1–5 of 139

Authors

542

  1. HM
    Hanns‐Christian Mahler

    Roche (Switzerland), Switzerland

    5 publications · 350 citations

    5

    h-index

  2. CC
    Chung C. Hsu

    Sunesis (United States), United States

    5 publications · 445 citations

    5

    h-index

  3. TA
    Tudor Arvinte

    University of Geneva, Switzerland

    4 publications · 247 citations

    4

    h-index

  4. MA
    Martinus A.H. Capelle

    University of Geneva, Switzerland

    3 publications · 217 citations

    3

    h-index

  5. SS
    Shreya S. Kulkarni

    University of Connecticut, United States

    3 publications · 86 citations

    3

    h-index

1–5 of 542

Institutions

201

  1. Roche (Switzerland)

    Basel, Switzerland

    5 h-index

    17 publications

    1.1K citations

  2. Amgen (United States)

    Thousand Oaks, United States

    5 h-index

    26 publications

    1.6K citations

  3. University of Connecticut

    Storrs, United States

    5 h-index

    11 publications

    433 citations

  4. University of Geneva

    Geneva, Switzerland

    4 h-index

    9 publications

    654 citations

  5. Ludwig-Maximilians-Universität München

    Munich, Germany

    4 h-index

    11 publications

    377 citations

  6. Center for Drug Evaluation and Research

    Silver Spring, United States

    4 h-index

    18 publications

    699 citations

  7. University of Lausanne

    Lausanne, Switzerland

    4 h-index

    7 publications

    560 citations

  8. Jiangnan University

    Wuxi, China

    3 h-index

    9 publications

    732 citations

1–8 of 201

Venues

  1. Journal of Pharmaceutical Sciences

    19 publications · 994 citations

    18

    h-index

  2. International Journal of Pharmaceutics

    14 publications · 885 citations

    13

    h-index

  3. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 10 publications · 669 citations

    10

    h-index

  4. Pharmaceutical Research

    7 publications · 538 citations

    7

    h-index

  5. Food Chemistry

    5 publications · 159 citations

    5

    h-index

1–5