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Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists

Brian Dyck, Liren Zhao, Junko Tamiya, Joseph Pontillo, Sarah Hudson, Brett Ching, Christopher E. Heise, Jenny Wen, Christi Norton, Ajay Madan,

Bioorganic & Medicinal Chemistry Letters · 2006 · 16 citations · 33 references

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33

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

Daqing Qu, David S. Ludwig, Steen Gammeltoft et al. · Nature · 1996 · 1.3K citations

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Mice lacking melanin-concentrating hormone are hypophagic and lean

Masako Shimada, Nicholas A. Tritos, Bradford B. Lowell et al. · Nature · 1998 · 1.2K citations

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Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

Donald J. Marsh, Drew T. Weingarth, Dawn E. Novi et al. · Proceedings of the National Academy of Sciences · 2002 · 551 citations

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Highly Active and Selective Catalysts for the Formation of α-Aryl Ketones

Joseph M. Fox, Xiaohua Huang, A. Chieffi et al. · Journal of the American Chemical Society · 2000 · 517 citations

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Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist

Beth Borowsky, Margaret M. Durkin, Kristine L. Ogozalek et al. · Nature Medicine · 2002 · 509 citations · Full text

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