Liren Zhao

A Thienopyridazinone-Based Melanin-Concentrating Hormone Receptor 1 Antagonist with Potent in Vivo Anorectic Properties

Brian Dyck, Stacy Markison, Liren Zhao et al. · Journal of Medicinal Chemistry · 2006 · 43 citations · Full text

Medicinal Chemistry, Pharmacological Study, Functional Selectivity +14

Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists

Jonathan Grey, Brian Dyck, Martin W. Rowbottom et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 22 citations · Full text

Functional Selectivity, Medicine, Mechanism Of Action +4

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists

Brian Dyck, Liren Zhao, Junko Tamiya et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 16 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +8

Synthesis and structure–activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)

Martin W. Rowbottom, Troy Vickers, Brian Dyck et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 15 citations · Full text

Molecular Pharmacology, Small-molecule Antagonists, Biochemistry +10

Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists

Chen Mi, Zhiqiang Guo, Marion Lanier et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 11 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +7