Joseph M. Fox

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

Melissa L. Blackman, Maksim Royzen, Joseph M. Fox · Journal of the American Chemical Society · 2008 · 1.6K citations · Full text

Pharmacy, Biochemistry, Biotechnology +12

Genetic Encoding of Bicyclononynes and <i>trans</i>-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

Kathrin Lang, Lloyd Davis, Stephen Wallace et al. · Journal of the American Chemical Society · 2012 · 524 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Highly Active and Selective Catalysts for the Formation of α-Aryl Ketones

Joseph M. Fox, Xiaohua Huang, A. Chieffi et al. · Journal of the American Chemical Society · 2000 · 517 citations

Natural Sciences, Chemistry, Catalysis +16

Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine– <i>trans-</i> Cyclooctene Ligation

Michael T. Taylor, Melissa L. Blackman, Olga Dmitrenko et al. · Journal of the American Chemical Society · 2011 · 346 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation

Ampofo Darko, Stephen Wallace, Olga Dmitrenko et al. · Chemical Science · 2014 · 277 citations

Natural Sciences, Chemistry, Computational Chemistry +10