Melissa L. Blackman

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

Melissa L. Blackman, Maksim Royzen, Joseph M. Fox · Journal of the American Chemical Society · 2008 · 1.6K citations · Full text

Pharmacy, Biochemistry, Biotechnology +12

Genetic Encoding of Bicyclononynes and <i>trans</i>-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

Kathrin Lang, Lloyd Davis, Stephen Wallace et al. · Journal of the American Chemical Society · 2012 · 524 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine– <i>trans-</i> Cyclooctene Ligation

Michael T. Taylor, Melissa L. Blackman, Olga Dmitrenko et al. · Journal of the American Chemical Society · 2011 · 346 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific <i>in Vivo</i> Bioorthogonal Ligation with <i>trans</i>-Cyclooctenes

Jason L. Seitchik, Jennifer C. Peeler, Michael T. Taylor et al. · Journal of the American Chemical Society · 2012 · 265 citations

Pharmacy, Biotechnology, Molecular Biology +13

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

Zibo Li, Hancheng Cai, Matthew Hassink et al. · Chemical Communications · 2010 · 192 citations

Pharmacy, Biotechnology, Medicinal Chemistry +15