Brett Ching

First-in-Class Pan Caspase Inhibitor Developed for the Treatment of Liver Disease

Steven D. Linton, Teresa Aja, Robert A. Armstrong et al. · Journal of Medicinal Chemistry · 2005 · 106 citations

Life Sciences, Pharmacokinetics, Pharmacology +14

Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI)

Dongpei Wu, Joseph Pontillo, Brett Ching et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists

Joseph R. Fotsing, Vincent Darmohusodo, Andrew Patron et al. · Journal of Medicinal Chemistry · 2020 · 19 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists

Brian Dyck, Liren Zhao, Junko Tamiya et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis and structure–activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2

Sarah Hudson, Mehrak Kiankarimi, Martin W. Rowbottom et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14