Fas-induced Activation of the Cell Death-related Protease CPP32 Is Inhibited by Bcl-2 and by ICE Family Protease Inhibitors

Robert C. Armstrong, Teresa Aja, Jialing Xiang, +8

Journal of Biological Chemistry

Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

Robert C. Armstrong, Teresa Aja, Kim Hoang, +7

Journal of Neuroscience

Ced3/ice-related Protease Cpp32ApoptosisGranule NeuronsCell DeathSocial Sciences +15

First-in-Class Pan Caspase Inhibitor Developed for the Treatment of Liver Disease

Steven D. Linton, Teresa Aja, Robert A. Armstrong, +35

Journal of Medicinal Chemistry

PathologyPharmacotherapyOxidative StressMedicinal ChemistryP4 Oxamides +16

Activation of Membrane-associated Procaspase-3 Is Regulated by Bcl-2

Joseph Krebs, Robert C. Armstrong, Anu Srinivasan, +13

The Journal of Cell Biology

Chemically programmed antibodies: Endothelin receptor targeting CovX-Bodies™

Venkata Ramana Doppalapudi, Nancy Tryder, Lingna Li, +7

Bioorganic & Medicinal Chemistry Letters

Molecular ImmunologyImmunologyProgrammed AntibodiesReceptor (Biochemistry)Vascular Biology +2

Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke

Steven D. Linton, Teresa Aja, Peter R. Allegrini, +20

Bioorganic & Medicinal Chemistry Letters

ThrombosisCardiovascular DiseaseMedicinePharmacologyStroke-related Condition +12

Long‐term protection of brain tissue from cerebral ischemia by peripherally administered peptidomimetic caspase inhibitors

Thomas L. Deckwerth, Lisa M. Adams, Peter R. Allegrini, +15

Drug Development Research

Cell DeathCerebrovascular DiseaseMagnetic Resonance ImagingCerebral Vascular RegulationThrombosis +20

Structure–Activity relationships within a series of caspase inhibitors: effect of leaving group modifications

Brett R. Ullman, Teresa Aja, Thomas L. Deckwerth, +13

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryBiochemistryMedicine +12

Structure–activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads

Brett R. Ullman, Teresa Aja, Ning Chen, +17

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyDrug TargetBiochemistryMedicineNatural Sciences +9