Dongpei Wu

Discovery of Sodium <i>R</i>-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2<i>H</i>-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor

Chen Chen, Dongpei Wu, Zhiqiang Guo et al. · Journal of Medicinal Chemistry · 2008 · 117 citations · Full text

Novel Uracil Phenylethylamines, Gynecology, Pharmacotherapy +16

Strength of conjugate binding to plasmid DNA affects degradation rate and expression level in vivo

Patricia M Mullen, Charles P. Lollo, Quynh-Chi Phan et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2000 · 53 citations

Chromatin, Genome Instability, Degradation Rate +11

A New Approach to the Stereospecific Synthesis of Phospholipids. The Use of <scp>l</scp>-Glyceric Acid for the Preparation of Diacylglycerols, Phosphatidylcholines, and Related Derivatives

Farzaneh S. Roodsari, Dongpei Wu, Gregory S. Pum et al. · The Journal of Organic Chemistry · 1999 · 41 citations

Lipid Analysis, Bioorganic Chemistry, Stereospecific Synthesis +18

Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor

Joseph Pontillo, Zhiqiang Guo, Dongpei Wu et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 32 citations

Gonadotropin-releasing Hormone Receptor, Hormonal Receptor, Medicine +2

Design and Structure−Activity Relationships of 2-Alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl)imidazolo[1,2-<i>a</i>]pyrimid-5-ones as Potent GnRH Receptor Antagonists

Yunfei Zhu, Zhiqiang Guo, Timothy D. Gross et al. · Journal of Medicinal Chemistry · 2003 · 31 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +16