Concepedia

A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells

Thomas Rauen, Y-T Juang, Christian M. Hedrich, Katalin Kis‐Tóth, George C. Tsokos

Genes and Immunity · 2012 · 20 citations · 13 references

DOI

Concepts

References

13

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

, , +17

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine · 2005 · 4K citations · Full text

, , +17

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Liang Zhou, Ivaylo I. Ivanov, Rosanne Spolski et al. · Nature Immunology · 2007 · 2.1K citations

, , +16

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

José C. Crispín, Mohamed Oukka, George Bayliss et al. · The Journal of Immunology · 2008 · 793 citations · Full text

, , +17