Concepedia

The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions

Stephen J. Tam, Ron Geller, Christoph Spiess, Judith Frydman

Nature Cell Biology · 2006 · 311 citations · 24 references

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24

Methods in Yeast Genetics

Heiner Jacob · Bioelectrochemistry and Bioenergetics · 1988 · 4.9K citations

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Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

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Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

Neil Bence, Roopal M. Sampat, Ron R. Kopito · Science · 2001 · 2.2K citations

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate, Siddhartha Mitra, Erik S. Schweitzer et al. · Nature · 2004 · 2K citations

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Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathology

Eberhard Scherzinger, Annie Sittler, Katja Schweiger et al. · Proceedings of the National Academy of Sciences · 1999 · 729 citations

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