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Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: Optimization of the 4-substituted piperidine

Christopher S. Burgey, Craig A. Stump, Diem N. Nguyen, James Z. Deng, Amy G. Quigley, Beth R. Norton, Ian M. Bell, Scott D. Mosser, Christopher Salvatore, Ruth Z. Rutledge,

Bioorganic & Medicinal Chemistry Letters · 2006 · 51 citations · 9 references

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9

Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine

Jes Olesen, Hans‐Christoph Diener, Ingo W. Husstedt et al. · New England Journal of Medicine · 2004 · 1.2K citations · Full text

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The CGRP-Antagonist, BIBN4096BS Does not Affect Cerebral or Systemic Haemodynamics in Healthy Volunteers

Steffen Birk, LH Lassen, Christina Kruuse et al. · Cephalalgia · 2005 · 181 citations

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Recognition of Privileged Structures by G-Protein Coupled Receptors

Kent Bondensgaard, Michael Ankersen, Henning Thøgersen et al. · Journal of Medicinal Chemistry · 2004 · 179 citations · Full text

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Development of Human Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonists. 1. Potent and Selective Small Molecule CGRP Antagonists. 1-[<i>N</i><sup>2</sup>-[3,5-Dibromo-<i>N</i>-[[4-(3,4-dihydro-2(1<i>H</i>)-oxoquinazolin-3-yl)-1- piperidinyl]carbonyl]-<scp>d</scp>-tyrosyl]-<scp>l</scp>-lysyl]-4-(4-pyridinyl)piperazine:  The First CGRP Antagonist for Clinical Trials in Acute Migraine

K Rudolf, Wolfgang Eberlein, Wolfhard Engel et al. · Journal of Medicinal Chemistry · 2005 · 78 citations · Full text

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Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead

Theresa M. Williams, Craig A. Stump, Diem N. Nguyen et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 52 citations · Full text

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