James Z. Deng

Copper-Facilitated Suzuki Reactions: Application to 2-Heterocyclic Boronates

James Z. Deng, Daniel V. Paone, Anthony T. Ginnetti et al. · Organic Letters · 2008 · 208 citations

Natural Sciences, Chemistry, Catalysis +13

Potent, Orally Bioavailable Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine:  Discovery of <i>N</i> -[(3 <i>R</i> ,6 <i>S</i> )-6-(2,3-Difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1 <i>H</i> -imidazo[4,5- <i>b</i> ]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974)

Daniel V. Paone, Anthony W. Shaw, Diem N. Nguyen et al. · Journal of Medicinal Chemistry · 2007 · 146 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Unraveling the Aflatoxin−FAPY Conundrum:  Structural Basis for Differential Replicative Processing of Isomeric Forms of the Formamidopyrimidine-Type DNA Adduct of Aflatoxin B₁

Kyle L. Brown, James Z. Deng, Rajkumar S. Iyer et al. · Journal of the American Chemical Society · 2006 · 72 citations · Full text

Life Sciences, Biochemistry, Biology +13

Synthesis of the (3<i>R</i>,6<i>S</i>)-3-Amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974), a Calcitonin Gene-Related Peptide Receptor Antagonist for the Treatment of Migraine Headache

Christopher S. Burgey, Daniel V. Paone, Anthony W. Shaw et al. · Organic Letters · 2008 · 61 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy

B. Wesley Trotter, Kausik K. Nanda, Christopher S. Burgey et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 59 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15