Daniel V. Paone

Direct Stereo- and Enantiocontrolled Synthesis of Vicinal Stereogenic Quaternary Carbon Centers. Total Syntheses of <i>meso</i>- and (−)-Chimonanthine and (+)-Calycanthine

Larry E. Overman, Daniel V. Paone, Brian A. Stearns · Journal of the American Chemical Society · 1999 · 221 citations

Engineering, Direct Stereo-, Heck Reaction +12

Copper-Facilitated Suzuki Reactions: Application to 2-Heterocyclic Boronates

James Z. Deng, Daniel V. Paone, Anthony T. Ginnetti et al. · Organic Letters · 2008 · 205 citations

Total Synthesis of (−)-Cylindrocyclophanes A and F Exploiting the Reversible Nature of the Olefin Cross Metathesis Reaction

Amos B. Smith, Christopher M. Adams, Sergey A. Kozmin et al. · Journal of the American Chemical Society · 2001 · 155 citations

Potent, Orally Bioavailable Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine:  Discovery of <i>N</i> -[(3 <i>R</i> ,6 <i>S</i> )-6-(2,3-Difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1 <i>H</i> -imidazo[4,5- <i>b</i> ]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974)

Daniel V. Paone, Anthony W. Shaw, Diem N. Nguyen et al. · Journal of Medicinal Chemistry · 2007 · 146 citations · Full text

Pharmacological Characterization of MK-0974 [N-[(3 R,6 S)-6-(2,3-Difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1 H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a Potent and Orally Active Calcitonin Gene-Related Peptide Receptor Antagonist for the Treatment of Migraine

Christopher Salvatore, James C. Hershey, Halea A. Corcoran et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 145 citations