Concepedia

Receptor Binding

Receptor Binding is a molecular recognition process in which an endogenous ligand or exogenous drug reversibly and specifically associates with a receptor macromolecule at defined binding sites, with characteristic affinity and kinetics that determine receptor occupancy and underlie the magnitude and specificity of subsequent pharmacological responses.

14.8K

Publications

1.1M

Citations

47.2K

Authors

4.9K

Institutions

Publications per year

2017–2026

1.4K

Variants

Ligand-receptor BindingReceptor Binding Studies

Parents

Children

Publications

14.8K

Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5.1K citations

, , +14

Structural basis of receptor recognition by SARS-CoV-2

Jian Shang, Gang Ye, Ke Shi et al. · Nature · 2020 · 4.1K citations · Full text

, , +17

Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices (Nobel Lecture)

Jean‐Marie Lehn · Angewandte Chemie International Edition in English · 1988 · 3.8K citations

, , +17

Identification of a major co-receptor for primary isolates of HIV-1

Hongkui Deng, Rong Liu, Wilfried Ellmeier et al. · Nature · 1996 · 3.7K citations

, , +11

High-Resolution Crystal Structure of an Engineered Human β <sub>2</sub> -Adrenergic G Protein–Coupled Receptor

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson et al. · Science · 2007 · 3.3K citations · Full text

, , +17

1–5 of 14.8K

Authors

47.2K

  1. RJ
    Robert J. Lefkowitz

    Duke Medical Center, United States

    131 publications · 26.9K citations

    87

    h-index

  2. BK
    Brian K. Kobilka

    Stanford University, United States

    72 publications · 19.3K citations

    57

    h-index

  3. MG
    Marc G. Caron

    Duke Medical Center, United States

    63 publications · 13K citations

    48

    h-index

  4. RC
    Raymond C. Stevens

    Scripps Research Institute, United States

    59 publications · 16.9K citations

    48

    h-index

  5. KA
    Kenneth A. Jacobson

    National Institutes of Health, United States

    102 publications · 8.2K citations

    44

    h-index

1–5 of 47.2K

Institutions

4.9K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    128 h-index

    845 publications

    195.4K citations

  2. National Institutes of Health

    Bethesda, United States

    102 h-index

    1.6K publications

    121.7K citations

  3. Duke Medical Center

    Durham, United States

    101 h-index

    809 publications

    130.9K citations

  4. Duke University Hospital

    Durham, United States

    94 h-index

    676 publications

    108.7K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    87 h-index

    1.7K publications

    136.8K citations

  6. Stanford University

    Stanford, United States

    83 h-index

    582 publications

    151.4K citations

  7. Harvard University

    Cambridge, United States

    78 h-index

    603 publications

    66.2K citations

  8. Inserm

    Paris, France

    78 h-index

    1.4K publications

    99.3K citations

1–8 of 4.9K

Venues

  1. Journal of Biological Chemistry

    JBC · 1.6K publications · 160.1K citations

    185

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 389 publications · 54.8K citations

    133

    h-index

  3. Nature

    181 publications · 86.8K citations

    132

    h-index

  4. Molecular Pharmacology

    677 publications · 50.9K citations

    107

    h-index

  5. Biochemistry

    527 publications · 31.8K citations

    88

    h-index

1–5