Concepedia

Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3)

Darby G. Brooke, Ellen M. van Dam, Colin K. W. Watts, Amanda Khoury, Marie Dziadek, Hilary Brooks, Lisa-Jane K. Graham, Jack U. Flanagan, William A. Denny

Bioorganic & Medicinal Chemistry · 2014 · 43 citations · 26 references

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References

26

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.7K citations

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On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.2K citations

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Substituent Constants for Correlation Analysis in Chemistry and Biology.

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Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

Rainer Wilcken, Markus O. Zimmermann, Andreas Lange et al. · Journal of Medicinal Chemistry · 2012 · 1.3K citations · Full text

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Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

Min Wu, Andy Neilson, Amy L. Swift et al. · American Journal of Physiology-Cell Physiology · 2006 · 920 citations

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