Markus O. Zimmermann

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

Rainer Wilcken, Markus O. Zimmermann, Andreas Lange et al. · Journal of Medicinal Chemistry · 2012 · 1.3K citations · Full text

Halogenation, Molecular Recognition, Medicinal Chemistry +15

Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53

Rainer Wilcken, Xiangrui Liu, Markus O. Zimmermann et al. · Journal of the American Chemical Society · 2012 · 229 citations · Full text

Molecular Biology, Chemical Biology, Mutant P53 +20

Using halogen bonds to address the protein backbone: a systematic evaluation

Rainer Wilcken, Markus O. Zimmermann, Andreas Lange et al. · Journal of Computer-Aided Molecular Design · 2012 · 100 citations

Protein Chemistry, Biochemistry, Protein Assembly +13

Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond

Andreas Lange, Marcel Günther, Felix Michael Büttner et al. · Journal of the American Chemical Society · 2015 · 80 citations

Gatekeeper Met146, Molecular Biology, Cell Death +24

Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases

Bassam Abu Thaher, Martina Arnsmann, Frank Totzke et al. · Journal of Medicinal Chemistry · 2011 · 73 citations · Full text