Frank Totzke

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

J M Wood, Guido Bold, Elisabeth Buchdunger et al. · PubMed · 2000 · 847 citations

Medicine, Oncology, Pharmacology +16

Roscovitine Targets, Protein Kinases and Pyridoxal Kinase

Stéphane Bach, Marie Knockaert, Jens Reinhardt et al. · Journal of Biological Chemistry · 2005 · 349 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Cytotoxic Metabolites from the Fungal Endophyte <i>Alternaria</i> sp. and Their Subsequent Detection in Its Host Plant <i>Polygonum senegalense</i>

Amal H. Aly, RuAngelie Edrada‐Ebel, Ine Dewi Indriani et al. · Journal of Natural Products · 2008 · 252 citations · Full text

Life Sciences, Botany, Pharmacology +15

Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1

Bernhard Barleon, Frank Totzke, Christel Herzog et al. · Journal of Biological Chemistry · 1997 · 197 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Bioactive Metabolites from the Endophytic Fungus <i>Stemphylium globuliferum</i> Isolated from <i>Mentha pulegium</i>

Abdessamad Debbab, Amal H. Aly, RuAngelie Edrada‐Ebel et al. · Journal of Natural Products · 2009 · 163 citations · Full text

Life Sciences, Botany, Plant Sciences +16