William A. Denny

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen et al. · Science Translational Medicine · 2011 · 569 citations

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

David W. Fry, Alexander J. Bridges, William A. Denny et al. · Proceedings of the National Academy of Sciences · 1998 · 417 citations

Drug Target, Cell Growth, Chemical Biology +21

Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor

Alexander J. Bridges, Hairong Zhou, Donna R. Cody et al. · Journal of Medicinal Chemistry · 1996 · 321 citations · Full text

Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kinetics

Juli Feigon, William A. Denny, Werner Leupin et al. · Journal of Medicinal Chemistry · 1984 · 279 citations

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo et al. · Journal of Medicinal Chemistry · 2000 · 263 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +21