Patrick D. Sutphin

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen et al. · Science Translational Medicine · 2011 · 569 citations

Regulation of p53 by Hypoxia: Dissociation of Transcriptional Repression and Apoptosis from p53-Dependent Transactivation

Constantinos Koumenis, Rodolfo Alarcón, Ester M. Hammond et al. · Molecular and Cellular Biology · 2001 · 346 citations · Full text

Dna Damage, Apoptosis, Cell Death +17

Role of Prolyl Hydroxylation in Oncogenically Stabilized Hypoxia-inducible Factor-1α

Denise A. Chan, Patrick D. Sutphin, Nicholas Denko et al. · Journal of Biological Chemistry · 2002 · 265 citations · Full text

Cancer Research, Biochemistry, Normoxic Hif-1alpha +13

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

Sandra Turcotte, Denise A. Chan, Patrick D. Sutphin et al. · Cancer Cell · 2008 · 252 citations · Full text

Cell Autophagy, Mitophagy, Medicine +7

Coordinate Regulation of the Oxygen-Dependent Degradation Domains of Hypoxia-Inducible Factor 1α

Denise A. Chan, Patrick D. Sutphin, Shing-Erh Yen et al. · Molecular and Cellular Biology · 2005 · 237 citations · Full text

Genetics, Hypoxia-inducible Factor 1α, Coordinate Regulation +18