Concepedia

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

Sandra Turcotte, Denise A. Chan, Patrick D. Sutphin, Michael P. Hay, William A. Denny, Amato J. Giaccia

Cancer Cell · 2008 · 254 citations · 57 references

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57

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

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Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress

Maiko Ogata, Shin‐ichiro Hino, Atsushi Saito et al. · Molecular and Cellular Biology · 2006 · 1.8K citations · Full text

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DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

Diane Crighton, Simon Wilkinson, Jim O’Prey et al. · Cell · 2006 · 1.4K citations · Full text

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