Michael P. Hay

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen et al. · Science Translational Medicine · 2011 · 579 citations

Medicine, Cancer Biology, Oncology +12

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

Sandra Turcotte, Denise A. Chan, Patrick D. Sutphin et al. · Cancer Cell · 2008 · 254 citations · Full text

Medicine, Cancer Biology, Oncology +10

Use of Three-Dimensional Tissue Cultures to Model Extravascular Transport and Predict In Vivo Activity of Hypoxia-Targeted Anticancer Drugs

Kevin O. Hicks, Frederik B. Pruijn, Timothy W. Secomb et al. · JNCI Journal of the National Cancer Institute · 2006 · 150 citations

Medicine, Pharmacokinetics, Pharmacology +16

Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors

Kevin O. Hicks, Bronwyn G. Siim, Jagdish K. Jaiswal et al. · Clinical Cancer Research · 2010 · 129 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Chemical Space Mimicry for Drug Discovery

William Yuan, Dadi Jiang, Dhanya K. Nambiar et al. · Journal of Chemical Information and Modeling · 2017 · 113 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +16