Gordon W. Rewcastle

Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor

Alexander J. Bridges, Hairong Zhou, Donna R. Cody et al. · Journal of Medicinal Chemistry · 1996 · 321 citations · Full text

Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II

William A. Denny, Gordon W. Rewcastle, Bruce C. Baguley · Journal of Medicinal Chemistry · 1990 · 309 citations

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo et al. · Journal of Medicinal Chemistry · 2000 · 263 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +21

Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5'-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor.

Gordon W. Rewcastle, William A. Denny, Alexander J. Bridges et al. · Journal of Medicinal Chemistry · 1995 · 259 citations · Full text

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling

Claire Chaussade, Gordon W. Rewcastle, Jackie D. Kendall et al. · Biochemical Journal · 2007 · 225 citations · Full text