Jeff B. Smaill

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

David W. Fry, Alexander J. Bridges, William A. Denny et al. · Proceedings of the National Academy of Sciences · 1998 · 417 citations

Drug Target, Cell Growth, Chemical Biology +21

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo et al. · Journal of Medicinal Chemistry · 2000 · 263 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +21

Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[<i>d</i>]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Jeff B. Smaill, Brian D. Palmer, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 1999 · 178 citations · Full text

The Horner-Wadsworth-Emmons Reaction in Natural Products Synthesis: Expedient Construction of Complex (<i>E</i>)-Enones Using Barium Hydroxide

Ian Paterson, Kap‐Sun Yeung, Jeff B. Smaill · Synlett · 1993 · 176 citations

Cross-coupling Reaction, Enantioselective Synthesis, Natural Products Synthesis +12

Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed

Y. Yosaatmadja, Shevan Silva, James M. Dickson et al. · Journal of Structural Biology · 2015 · 145 citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +9