William A. Denny

Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5'-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor.

Gordon W. Rewcastle, William A. Denny, Alexander J. Bridges et al. · Journal of Medicinal Chemistry · 1995 · 259 citations · Full text

Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids

Gordon W. Rewcastle, Graham J. Atwell, Li Zhuang et al. · Journal of Medicinal Chemistry · 1991 · 194 citations

Implanted Colon 38, Medicinal Chemistry, Bioorganic Chemistry +15

DNA-intercalating ligands as anti-cancer drugs: prospects for future design.

William A. Denny · PubMed · 1989 · 162 citations

Dna Nanotechnology, Medicinal Chemistry, Polymer-drug Conjugate +12

Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as minimal DNA-intercalating antitumor agents with in vivo solid tumor activity

Graham J. Atwell, Bruce C. Baguley, William A. Denny · Journal of Medicinal Chemistry · 1989 · 157 citations

Tyrosine kinase inhibitors. 7. 7-amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidines: a new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor

Andrew M. Thompson, Alexander J. Bridges, David W. Fry et al. · Journal of Medicinal Chemistry · 1995 · 141 citations · Full text