Concepedia

Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic Study of 277 patients

Mrinal M. Patnaik, Curtis A. Hanson, Janice M. Hodnefield, Terra L. Lasho, Christy M. Finke, Ryan A. Knudson, Rhett P. Ketterling, Animesh Pardanani, Ayalew Tefferi

Leukemia · 2011 · 145 citations · 26 references

DOI

Concepts

References

26

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

D. Williams Parsons, Siân Jones, Xiaosong Zhang et al. · Science · 2008 · 5.8K citations · Full text

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text

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Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

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Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

Elaine R. Mardis, Li Ding, David J. Dooling et al. · New England Journal of Medicine · 2009 · 2.2K citations · Full text

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The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Patrick S. Ward, Jay Patel, David R. Wise et al. · Cancer Cell · 2010 · 2K citations · Full text

, , +12