Concepedia

AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

Cecilia Grimaldi, Francesca Chiarini, Giovanna Tabellini, Francesca Ricci, Pier Luigi Tazzari, Michela Battistelli, Elisabetta Falcieri, Roberta Bortul, Fraia Melchionda, Ilaria Iacobucci,

Leukemia · 2011 · 94 citations · 39 references

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References

39

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung, Chang Jun, Seung‐Hyun Ro et al. · Molecular Biology of the Cell · 2009 · 2K citations · Full text

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A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

Akseli Hemminki, David Markie, Ian Tomlinson et al. · Nature · 1998 · 1.6K citations

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Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

Heather A. Hirsch, Dimitrios Iliopoulos, Philip N. Tsichlis et al. · Cancer Research · 2009 · 1.1K citations · Full text

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