Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

Fraia Melchionda, Terry J. Fry, Matthew Milliron, +3

Journal of Clinical Investigation

Il-15 Overcomes ImmunodominanceT Cell MemoryImmunologyImmunodominanceMemory Pools +14

Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

Fraia Melchionda, Terry J. Fry, Matthew Milliron, +3

Journal of Clinical Investigation

Activity of the Novel Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 against T-Cell Acute Lymphoblastic Leukemia

Francesca Chiarini, Cecilia Grimaldi, Francesca Ricci, +10

Cancer Research

Pi3k/akt/mtor NetworkMixed-phenotype Acute LeukemiaImmunologyImmunotherapyTumor Biology +14

Multicenter randomized, double‐blind controlled trial to evaluate the efficacy of laser therapy for the treatment of severe oral mucositis induced by chemotherapy in children: laMPO RCT

Margherita Gobbo, Federico Verzegnassi, Luca Ronfani, +18

Pediatric Blood & Cancer

Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia

Camilla Evangelisti, Francesca Ricci, Pier Luigi Tazzari, +10

Leukemia

Hematological MalignancyCytotoxic EffectsMedicineMixed-phenotype Acute LeukemiaMalignant Blood Disorder +7

AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

Cecilia Grimaldi, Francesca Chiarini, Giovanna Tabellini, +13

Leukemia

Signal TransductionSignaling PathwayMixed-phenotype Acute LeukemiaAmp-dependent Kinase/mammalian TargetMalignant Blood Disorder +7

Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia

Carolina Simioni, Luca M. Neri, Giovanna Tabellini, +12

Leukemia

Hematological MalignancyNovel Akt InhibitorMedicineMixed-phenotype Acute LeukemiaMalignant Blood Disorder +6

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Francesca Buontempo, Ester Orsini, Leila R. Martins, +14

Leukemia

Hematological MalignancyInhibitor Cx-4945Receptor Tyrosine KinaseMalignant Blood DisorderImmunology +8

Diagnosis of bloodstream infections in immunocompromised patients by real-time PCR

Stefania Varani, Marta Stanzani, Michela Paolucci, +7

Journal of Infection

Real-time PcrHealthcare-associated InfectionHematologyDiagnosisDiagnostic Test +5

Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma

Melinda S. Merchant, Xuezhong Yang, Fraia Melchionda, +6

Cancer Research

ApoptosisImmunologyPathologyCell DeathSelective Apoptosis +15