Heather A. Hirsch

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

Dimitrios Iliopoulos, Heather A. Hirsch, Kevin Struhl · Cell · 2009 · 1.4K citations · Full text

Inflammation, Cytokine, Let-7 Microrna +14

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

Heather A. Hirsch, Dimitrios Iliopoulos, Philip N. Tsichlis et al. · Cancer Research · 2009 · 1.1K citations · Full text

Cancer Biology, Cancer Stem, Xenograft Mouse Model +16

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

Dimitrios Iliopoulos, Savina Jaeger, Heather A. Hirsch et al. · Molecular Cell · 2010 · 822 citations · Full text

Inflammation, Medicine, Immunology +10

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

Dimitrios Iliopoulos, Heather A. Hirsch, Guannan Wang et al. · Proceedings of the National Academy of Sciences · 2011 · 637 citations · Full text

Non-stem Cancer Cells, Breast Oncology, Prostate Cscs +21

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

Dimitrios Iliopoulos, Heather A. Hirsch, Kevin Struhl · Cancer Research · 2011 · 444 citations · Full text

Tumor Biology, Cancer Relapse, Medicine +11