Roberta Bortul

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

Alberto M. Martelli, Pier Luigi Tazzari, Giovanna Tabellini et al. · Leukemia · 2003 · 152 citations · Full text

Hematological Malignancy, All-trans-retinoic Acid, Medicine +11

Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia

Camilla Evangelisti, Francesca Ricci, Pier Luigi Tazzari et al. · Leukemia · 2011 · 101 citations · Full text

Hematological Malignancy, Cytotoxic Effects, Medicine +9

Diacylglycerol kinase-θ is localized in the speckle domains of the nucleus

Giovanna Tabellini, Roberta Bortul, Spartaco Santi et al. · Experimental Cell Research · 2003 · 97 citations · Full text

Developmental Biology, Signal Transduction, Diacylglycerol Kinase-θ +9

AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

Cecilia Grimaldi, Francesca Chiarini, Giovanna Tabellini et al. · Leukemia · 2011 · 94 citations · Full text

Signal Transduction, Signaling Pathway, Mixed-phenotype Acute Leukemia +9

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-κB activation and cFLIPL up-regulation

Roberta Bortul, Pier Luigi Tazzari, Alessandra Cappellini et al. · Leukemia · 2003 · 93 citations

Signal Transduction, Signaling Pathway, Cell Regulation +12