Concepedia

1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Alexander L. Ruchelman, Hon‐Wah Man, Roger Chen, Wei Liu, Ling Lu, Dorota Cedzik, Ling Zhang, Jim Leisten, Alice Collette, Rama Krishna Narla,

Bioorganic & Medicinal Chemistry · 2011 · 28 citations · 43 references

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43

N-methoxy-n-methylamides as effective acylating agents

Steven Nahm, Steven M. Weinreb · Tetrahedron Letters · 1981 · 1.8K citations

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Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain

Raimond B. G. Ravelli, Benoı̂t Gigant, Patrick A. Curmi et al. · Nature · 2004 · 1.6K citations

, , +14

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 789 citations

, , +11

Palladium-catalysed vinylation of organic halides under solid–liquid phase transfer conditions

Tuyêt Jeffery · Journal of the Chemical Society Chemical Communications · 1984 · 465 citations

, , +5

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

Chii M. Lin, Holly H. Ho, George R. Pettit et al. · Biochemistry · 1989 · 414 citations

, , +17