Rama Krishna Narla

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

Joshua D. Hansen, Matthew Correa, Mark A. Nagy et al. · Journal of Medicinal Chemistry · 2020 · 204 citations · Full text

Hematological Malignancy, Novel Therapy, Medicine +15

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

Patrick R. Hagner, Hon‐Wah Man, Celia Fontanillo et al. · Blood · 2015 · 197 citations · Full text

Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents.

E. Sudbeck, Xingping Liu, Rama Krishna Narla et al. · PubMed · 1999 · 165 citations

Drug Target, Bioorganic Chemistry, Apoptosis +21

CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia

Joshua D. Hansen, Matthew Correa, Matt Alexander et al. · Journal of Medicinal Chemistry · 2021 · 138 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Cell Death +17

The Synthetic Compound CC-5079 Is a Potent Inhibitor of Tubulin Polymerization and Tumor Necrosis Factor-α Production with Antitumor Activity

Linghua Zhang, Lei Wu, Heather K. Raymon et al. · Cancer Research · 2006 · 90 citations

Antitumor Activity, Chemoprevention Strategy, Immunology +20