George R. Pettit

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 783 citations

Natural Sciences, Molecular Biology, Cytoskeleton +8

Isolation and structure of bryostatin 1

George R. Pettit, Cherry L. Herald, Dennis L. Doubek et al. · Journal of the American Chemical Society · 1982 · 652 citations

Bioorganic Chemistry, Chemical Analysis, Altmetric Attention Score +25

Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature.

G. Dark, S A Hill, Vivien E. Prise et al. · PubMed · 1997 · 624 citations

Vascular Shutdown, Tumor Biology, Oncology +16

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

George R. Pettit, Yoshiaki Kamano, Cherry L. Herald et al. · Journal of the American Chemical Society · 1987 · 573 citations

Biology, Dolastatin 10George, Marine Biotechnology +14

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

Chii M. Lin, Holly H. Ho, George R. Pettit et al. · Biochemistry · 1989 · 412 citations

Chromatin, Medicinal Chemistry, Molecular Pharmacology +15