George R. Pettit

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 789 citations

Life Sciences, Biochemistry, Cell Biology +11

Isolation and structure of bryostatin 1

George R. Pettit, Cherry L. Herald, Dennis L. Doubek et al. · Journal of the American Chemical Society · 1982 · 655 citations

Natural Sciences, Biochemistry, Chemistry +6

Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature.

G. Dark, S A Hill, Vivien E. Prise et al. · PubMed · 1997 · 624 citations

Medicine, Oncology, Pharmacology +13

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

George R. Pettit, Yoshiaki Kamano, Cherry L. Herald et al. · Journal of the American Chemical Society · 1987 · 577 citations

Pharmacy, Toxicology, Analytical Toxicology +10

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

Chii M. Lin, Holly H. Ho, George R. Pettit et al. · Biochemistry · 1989 · 414 citations

Medicine, Medicinal Chemistry, Pharmacology +17