Nature Medicine · 2011 · 344 citations · 48 references
Life SciencesMolecular BiologyNeuroscienceMolecular NeurobiologyMolecular NeuroscienceNeurodegenerationEpigenetic Regulation In NeuronsHuntington DiseaseMolecular Basis Of NeurodegenerationNeurodegenerative DiseasesNeurodegenerative DisordersNeuroprotectionHuntington Disease EpigeneticsHuntington Disease NeuroprotectionHuntington's Disease ModelsNeuroprotective MechanismsNeuroprotective SignalingSirtuin 1 RegulationSirtuin Pathways
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Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
Anne Brunet, Lora B. Sweeney, James Fitzhugh Sturgill et al. · Science · 2004 · 3.2K citations
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
Joseph T. Rodgers, Carles Lerín, Wilhelm Haas et al. · Nature · 2005 · 3.1K citations
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text