Mali Jiang

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

Mali Jiang, Jiawei Wang, Jinrong Fu et al. · Nature Medicine · 2011 · 344 citations

Life Sciences, Molecular Biology, Neuroscience +16

trans-(−)-ε-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease

Jinrong Fu, Jing Jin, Robert H. Cichewicz et al. · Journal of Biological Chemistry · 2012 · 209 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model

Peng Qi, Naoki Masuda, Mali Jiang et al. · Experimental Neurology · 2007 · 173 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington’s Disease

Peng Qi, Bin Wu, Mali Jiang et al. · PLoS ONE · 2016 · 136 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease

Mali Jiang, Xinfeng Liu, Jian Jin et al. · Human Molecular Genetics · 2013 · 129 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17