The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production

<i>Principles of Nuclear Magnetic Resonance in One and Two Dimensions</i>

Richard R. Ernst, Geoffrey Bodenhausen, Alexander Wokaun et al. · Physics Today · 1989 · 4.2K citations

Natural Sciences, Chemistry, Physics +17

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +16

Neurodegenerative Tauopathies

Virginia M.‐Y. Lee, Michel Goedert, John Q. Trojanowski · Annual Review of Neuroscience · 2001 · 2.4K citations

Life Sciences, Neurology, Neuroscience +16

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17